BDBM557846 1-(4-((4-((2,4-dichlorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-prop-2-en-1-one::US11365189, Ex. No. 1

SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OC1CCN(CC1)C(=O)C=C

InChI Key InChIKey=RJKRKHCTOQGWQU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557846   

TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557846(1-(4-((4-((2,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent